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Folaţii sunt compuşi ai acidului pteroilglutamic, care funcţionează ca şi coenzime în reacţii metabolice care implică transferul unei unităţi de carbon. Folaţii şi vitamina B12 sunt esenţiali。

Diagnosticul de laborator al deficitului de acid folic include măsurarea acidului folic seric și a celui eritrocitar. În sânge, 95 % din acidul folic este în eritrocite. Prin urmare acidul folic eritrocitar。

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